獣医病理学研究室

Laboratory of Veterinary Pathology

 

牛、馬、豚、鷄などの産業動物や、犬、猫などの小動物、ウサギ、ハムスター、フェレットなどのエキゾチックアニマル、さらに野生動物などに発生する様々な病変の起こる原因や経過、結果などを病理解剖学的、病理組織学的に明らかにしています。また、電子顕微鏡や免疫組織化学さらに分子生物学的な手法を用いて病気の本態に迫る研究を展開しています。

 

教員

教授  佐藤常男 Professor Tsuneo SATO

准教授 渋谷 久 Associate Professor Hisashi SHIBUYA

 

大学院学生

1年生 1

 

学部学生

6年生 5名 5年生 9名 4年生 13

 

主な研究課題

動物腫瘍の病理学的研究

動物の遺伝性疾患の研究

希少症例の病理学的検索

 

研究業績(Selected papers)

N. Kido, K. Edamura, N. Inoue, H. Shibuya, T. Sato, M. Kondo, I. Shindo. Perivertebral B-cell lymphoma in a Queenland Koala (Phascolarctos cinereus adustus) with paralytic symptoms in the hind limbs. Journal of Veterinary Medical Science, 74: 1029-1032 (2012).

 

M. Ishikawa, H. Kondo, M Onuma, H Shibuya, T Sato. Osteoblastic osteosarcoma in a rabbit. Comparative Medicine, 62: 124-126 (2012).

 

K. Ito, Y. Yamaya, K. Asano, T. Sano, T. Watari, H. Shibuya, T. Sato, S. Tanaka. A case of pulomonary aspergilloma in a Border Collie. 獣医麻酔外科誌, 42: 13-16 (2011).

 

H. Kondo, M. Onuma, H. Shibuya, T. Sato, J. R. Abbott. Atypical fibrosarcoma derived from cutaneous ganglion cell-like cells in two domestic Djungarian hamsters (Phodopus sungorus). Journal of the American Association for Laboratory Animal Science. 50: 523-525 (2011).

 

T. Ito, R. Kano, H. Sobukawa, J. Ogawa, Y. Honda, Y. Hosoi, H. Shibuya, T. Sato, A. Hasegawa, H. Kamata. Experimental infection ob bovine mammary gland with Prototheca zopfii genotype 1. Journal of Veterinary Medical Science, 73: 117-119 (2011).

 

M. Onuma, S. Ono, T. Ishida, H. Shibuya, T. Sato. Radiographic measurement of cardiac size in 27 rabbits. Journal of Veterinary Medical Science, 72: 529-531 (2010).

 

小沼 守、小野貞治、石田智子、渋谷 久、佐藤常男.フェレットの消化管閉塞を併発した慢性膵炎の1例.日本獣医師会誌、63205-2072010).

 

小沼 守、近藤広孝、小野貞治、渋谷 久、佐藤常男.フェレットのリンパ腫12例における血液検査所見の回顧的検討.動物臨床医学、1847522010).

 

小沼 守、近藤広孝、石川 愛、小野貞治、上木万里子、石田智子、渋谷 久、佐藤常男.部分的中枢性尿崩症のウサギの1例.日本獣医師会誌、627177192009).

 

小沼 守、近藤広孝、石川 愛、小野貞治、上木万里子、渋谷 久、佐藤常男.ウサギの縦隔型リンパ腫におけるロムスチン使用1症例.日本獣医師会誌、6269712009).

 

M. Onuma, H. Kondo, S. Ono, M. Ueki, H. Shibuya, T. Sato. Radiographic measurement of cardiac size in 64 ferrets. Journal of Veterinary Medical Science, 71: 355-358 (2009).

 

小沼 守、近藤広孝、小野貞治、上木万里子、渋谷 久、佐藤常男.ロムスチンによるレスキュー療法を行ったフェレットの消化器型リンパ腫の1症例.日本獣医師会誌、61、7177192008).

小沼 守、近藤広孝、小野貞治、上木万里子、渋谷 久、佐藤常男.フェレットの皮膚血管肉腫の1例.日本獣医師会誌、61、3033052008).

 

H Maeda, H Shibuya, Y Yamaguchi, T Miyoshi, M Irie, T Sato. Feline digital phaeopyphomycosis due to Exophiala jeanselmei. Journal of Veterinary Medical Science, 70: 1395-1397 (2008).

 

H. Kondo, M. Onuma, H. Ito, H. Shibuya, T. Sato. Spontaneous fibrosarcoma in a Djungarian hamster (Phodopus sungorus). Comparative Medicine, 58: 294-296 (2008).

 

H. Kondo, M. Onuma, H. Shibuya, T. Sato. Spontaneous tumors in domestic hamsters. Veterinary Pathology, 45: 674-680 (2008).

 

M. Ishikawa, H. Maeda, H. Kondo, H. Shibuya, M. Onuma, T. Sato. A case of lymphoma developing in the rabbit cecum. Journal of Veterinary Medical Science, 69: 1183-1185 (2007).

 

H. Kondo, M. Ishikawa, H. Maeda, M. Onuma, M. Masuda, H. Shibuya, H. Koie, T. Sato. Spontaneous osteosarcoma in a rabbit (Oryctolagus cuniculus). Veterinary Pathology, 44: 691-694 (2007).

 

M. Okada, M. Kitagawa, H. Shibuya, K. Kanayama, T. Sato, H. Yamamura, T. Sakai. Malignant peripheral nerve sheath tumor arising from the spinal canal in a cat. Journal of Veterinary Medical Science, 69: 683-686 (2007).

 

T. Sato, H. Maeda, A. Suzuki, H. Shibuya, A. Sakata, W. Shirai: Endometrial stromal sarcoma with smooth muscle and glandular differentiation of the feline uterus, Veterinary Pathology, 47: 379-382 (2007)..

 

H. Tamaizumi, H. Kondo, H. Shibuya, M. Onuma, T. Sato: Tail root osteosarcoma in a chipmunk (Tamias sibiricus), Veterinary Pathology. 44: 392-394 (2007)..

 

K. Takada, K. Hayashi, K. Sasaki, T. Sato, M. Hirasawa: Selectivity of Mitis Salivarius agar and a new selective medium for oral streptocooci in dogs, Journal of Microbiological Methods, 66 (3), 460-465 (2006).

 

M. Okada, H. Koie, M. Kitagawa, K. Kanayama, T. Sato, H. Yamamura, T. Sakai: MRI findings of haematomyelia in a dog with spontaneous systemic haemorrhage, Australian Veterinary Journal, 84 (9), 332-335 (2006).

 

M. Sakai, K. Harada, H. Matsumura, T. Takahashi, H. Koie, Y. Yamaya, T. Watari, H. Shibuya, T. Sato, M. Tokuriki, A. Hasegawa: A case of feline pancreatitis. Journal of Veterinary Medical Science, 68 (12), 1331-1333 (2006).

 

M. Sakai, I. Otani, K. Ishigaki, K. Edamura, T. Takahashi, H. Koie, Y. Yamaya, T. Watari, H. Shibuya, T. Sato, K. Kanayama, M. Tokuriki, A. Hasegawa: Phenotypic analysis of hepatic T lymphocytes in a dog with chronic hepatitis. Journal of Veterinary Medical Science, 68 (11), 1219-1221 (2006).

 

K. Asano, A. Sakata, H. Shibuya, M. Kitagawa, K. Teshima, Y. Kato, Y. Sasaki, K. Kutara, M. Seki, K. Edamura, T. Sato, S. Tanaka: Fibrodysplasia ossificans progressiva-like condition in a cat, Journal of Veterinary Medical Science, 68 (9), 1003-1006 (2006).

 

K. Kutara, K. Asano, A. Kito, K. Teshima, Y. Kato, Y. Sasaki, K. Edamura, H. Shibuya, T. Sato, A. Hasegawa, S. Tanaka: Contrast harmonic imaging of canine hepatic tumors, Journal of Veterinary Medical Science, 68 (5), 433-438 (2006).

 

M. Sakai, K. Asano, M. Nakata, T. Takahashi, H. Koie, Y. Yamaya, T. Watari, H. Shibuya, T. Sato, M. Tokuriki, A. Hasegawa: Diabetes mellitus after resection of hepatocellular carcinoma with hypoglycemia in a dog, Journal of Veterinary Medical Science, 68 (7), 765-767 (2006).

 

Y. Kato, K. Asano, I. Mizutani, T. Konno, Y. Sasaki, K. Kutara, K. Teshima, K. Edamura, R. Kano, K. Suzuki, H. Shibuya, T. Sato, A. Hasegawa, S. Tanaka: Gene expressions of canine angiopoietin-1 and -2 in normal tissues and spontaneous tumours, Research in Veterinary Science, 81: 280-286 (2006).

 

K. Kutara, K. Asano, A. Kito, K. Teshima, Y. Kato, Y. Sasaki, K. Edamura, H. Shibuya, T. Sato, A. Hasegawa, S. Tanaka: Contrast harmonic imaging of canine hepatic tumors, Journal of Veterinary Medical Science, 68: 433-438 (2006).

 

W. Shirai, T. Sato, H. Shibuya, K. Naito and A. Tsukise: Anatomicopathological study of vascular and biliary systems using cast samples of Fasciola-infected bovine livers, Journal of Veterinary Medicine A, 53, 239-245 (2006).

 

H. Gotoh, K. Harada, K. Suzuki, S. Hashimoto, H. Yamamura, T. Sato, K. Fukumoto, H. Hagiwara, T. Ishida, K. Yamada, R. Asano, T. Yano: Expression patterns of connexin 26 and conexin 43 mRNA in canine benign and malignant mammary tumors, The Veterinary Journal, 172, 178-180 (2006).

 

H. Kondo, M. Takeda, H. Shibuya, W. Shirai, K. Matsuo, T. Sato: Cutaneous plasmacytoma in three hamsters (Mesocrietus auratus), Journal of Veterinary Medicine A, 53, 74-76 (2005).

 

T. Sato, J. Ito, H. Shibuya, K. Asano, T. Watari: Pulmonary Adenosquamous Carcinoma in a Dog, Journal of Veterinary Medicine A, 52, 510-513 (2005).

 

W. Shirai, T. Sato, H. Shibuya, K. Naito, A. Tsukise: Three-dimensional Vasculature of the Bovine Liver, Anatomia, Histologia, Embryologia, 34, 354-363 (2005).

 

H. Maruyama, T. Watari, T. Miura, M. Sakai, T. Takahashi, H. Koie, Y. Yamaya, K. Asano, K. Edamura, T. Sato, S. Tanaka, A. Hasegawa, M. Tokuriki: Plasma thrombin-antithrombin complex concentration in dogs with malignant tumours, TheVeterinary Record, 156, 839-840 (2005).

 

H. Maeda, H. Shibuya, K. Suzuki, M. Kuwabara, A. Tsukise, T. Sato: A Case of Anaplastic meningioma in a Dog, The Journal of Veterinary Medical Science, 67, 1177-1180 (2005).

 

T. Sato, A. Yamamoto, H. Shibuya, H. Sudo, W. Shirai, T. Amemori: Intraocular peripheral nerve sheath tumor in a dog, Veterinary Ophthalmology, 8, 283-286 (2005).

 

H. Kondo, T. Sato, H. Shibuya, M. Onuma: Subcutaneous angiolipoma of abdomen in a golden hamster (Mesocrietus auratus), Journal of Veterinary Medicine A, 52, 395-396 (2005).

 

S. Saito, K. Suzuki, H. Shibuya, T. Yamaguchi, T. Sato: Melanocytic Matricoma in a Dog, Veterinary Pathology, 42, 499-502 (2005).

 

T. Sato, T. Miyoshi, H. Shibuya, J. Fujikura, H. Koie, Y. Miyazaki: Peritoneal Biphasic Mesothelioma arising in a Dog, Journal of Veterinary Medicine A, 52, 22-25 (2005).

 

M. Kitagawa, K. Kanayama, T. Sato, T. Sakai: Cerebellar Focal Granulomatous Meningoencephalitis in a Dog: Clinical Findings and MR Imaging, Journal of Veterinary Medicine A, 51, 277-279 (2004).

 

H. Koie, H. Shibuya, T. Sato, A. Sato, K. Nawa, Y. Nawa, K. Kitagawa, M. Sakai, T. Takahashi, Y. Yamaya, O. Yamato, T. Watari, M. Tokuriki: Magnetic Resonance Imaging of Neuronal Ceroid Lipofuscinosis in the Border Collie, The Journal of Veterinary Medical Science, 66, 1453-1456 (2004).

 

Y. Yamaguchi, T. Sato, H. Shibuya, S. Tsumagari, T. Suzuki: Ovarian Teratoma with a Formed Lens and Nonsuppurative Inflammation in an Old Dog, The Journal of Veterinary Medical Science, 66, 861-864 (2004).

 

T. Miura, H. Maruyama, M. Sakai, T. Takahashi, H. Koie, Y. Yamaya, H. Shibuya, T. Sato, T. Watari, M. Tokuriki, A. Hasegawa: Endoscopic  Findings on Alimentary Lymphoma in 7 Dogs, The Journal of Veterinary Medical Science,  66 , 577-580 (2004).

 

H. Maruyama, T. Miura, M. Sakai, H. Koie, Y. Yamaya, H. Shibuya, T. Sato, T. Watari, A. Takeuchi, M. Tokuriki, A. Hasegawa: The Incidence of Disseminated Intravascular Coagulation in Dogs with Malignant Tumor, The Journal of Veterinary Medical Science, 66 , 573-575 (2004).

 

T. Sato, M. Takada, H. Shibuya, W. Shirai, K. Matsuo: A Malar Granular Cell Tumor in a Djungarian Hamster, Journal of Veterinary Medicine A, 51, 23-26 (2004).

 

T. Sato, H. Koie, H. Shibuya, K. Suzuki: Extraskeletal Osteosarcoma in the Pericardium of a Dog, The Veterinary Record, 155, 780-781(2004).

 

T. Sato, K. Aoki, H. Shibuya, T. Machida, T. Watari: Leiomyosarcoma of the Kidney in a Dog, Journal of Veterinary Medicine A, 50, 366-369 (2003).

 

T. Sato, S. Hontake, H. Shibuya, W. Shirai, T. Yamaguchi: A Solid Mature Teratoma of Feline Ovary, Journal of Feline Medicine and Surgery, 5, 349-35 (2003).

 

T. Sato, A. Nakamura, H. Shibuya, W. Shirai, H. Koie: Cerebral high-grade astrocytoma (Glioblastoma) in a Cat, Journal of Veterinary Medicine A, 50, 269-271 (2003).

 

T. Sato, H. Shibuya, S. Ohba, T. Nojiri, W. Shirai: Mycobacteriosis in two Captive Florida Manaties (Trichechus Manatus Latirostris), Journal of Zoo and Wildlife Medicine, 34,184-188 (2003).

 

T. Sato, Y. Ikebata, H. Koie, H. Shibuya, W. Shirai, S. Nogami: Magnetic Resonance Imaging and Pathological Findings in a Cat with Brain Contusions, Journal of Veterinary Medicine A, 50, 222-223 (2003).

 

M. Sakai, I. Otani, T. Watari, T. Sato, K. Kanayama, A. Takeuchi, A. Hasegawa: Phenotypic Analysis of Hepatic Lymphocytes from Healthy Dogs, The Journal of Veterinary Medical Science, 65, 157-159 (2003).

 

M. Kawamorita, C. Suzuki, G. Saito, T. Sato, K. Sato: In Vitro Differentiation of Mouse Embryonic Stem Cells after Activation by Retinoic Acid, HUMAN CELL, 15, 178-182 (2002).

 

C. S. Leok, I. Inoue, T. Sato, M. Haritani, N. Tanimura, K. Okada: Pathological Observation of Indonesian Village Chickens Infected with Oviduct Fluke Prosthogonimus ovatus and Morphological Observation of Isolated Flukes, The Journal of Veterinary Medical Science, 64, 1129-1131 (2002).

 

T. Sato, T. Higuchi, H. Shibuya, S. Ohba, S. Nogami, W. Shirai, H. Watanabe and S. Honda: Lingual Squamous Cell Carcinoma in a California Sea Lion (Zalophus Californianus), Journal of Zoo and Wildlife Medicine, 33, 367-370 (2002).

 

T. Sato, K. Tezuka, H. Shibuya, T. Watanabe, H. Kamata, and W. Shirai: Cold-induced Ascites in Broiler Chickens and Its Improvement by Temperature Controlled Rearing, Avian Diseases, 46, 989-996 (2002).

 

T. Sato, E. Nosaka, H. Shibuya, E. Momotani, Y. Fujii, J. Inoue, K. Tezuka and W. Shirai: Myxoid Leiomyosarcoma of the Gizzard in a Broiler,  Avian Diseases, 46, 256-259 (2002).

 

M. Kuwabara, M. Kitagawa, T.Sato, S. Ohba and T. Tsubokawa: Early diagnosis of feline medulloblastoma in the vermis, The Veterinary Record, 150, 488-489 (2002).